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Also, BPC 157 was given perorally in drinking water for 4 weeks (12 ml/rat/day, 0.16 g/ml, 0.16 ng/ml) in rats which underwent ibuprofen application for 4 weeks while controls were drinking water only

These results indicate that no specific dose adjustment for cagrilintide is required for people with renal or hepatic impairment

Systemic effects less commonly include mild dizziness or lightheadedness (may be copper-related), temporary nausea or headache (typically resolves within hours), mild fatigue (rare, reported with higher doses), and transient flu-like symptoms (very rare, may relate to systemic inflammatory response)

When administered under licensed medical supervision using pharmaceutical-grade compounds, the combination has a well-documented safety profile